Xavier Hébuterne Selected Research

ontamalimab

1/2022	Long-Term Safety and Efficacy of the Anti-Mucosal Addressin Cell Adhesion Molecule-1 Monoclonal Antibody Ontamalimab (SHP647) for the Treatment of Crohn's Disease: The OPERA II Study.
6/2021	Long-term Safety and Efficacy of the Anti-MAdCAM-1 Monoclonal Antibody Ontamalimab [SHP647] for the Treatment of Ulcerative Colitis: The Open-label Study TURANDOT II.
10/2018	Phase II evaluation of anti-MAdCAM antibody PF-00547659 in the treatment of Crohn's disease: report of the OPERA study.
1/2017	Anti-MAdCAM antibody (PF-00547659) for ulcerative colitis (TURANDOT): a phase 2, randomised, double-blind, placebo-controlled trial.

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Xavier Hébuterne Research Topics

Disease

25	Crohn Disease (Crohn's Disease) 07/2022 - 11/2002
10	Ulcerative Colitis 06/2022 - 09/2011
7	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2020 - 02/2011
7	Intestinal Failure 04/2015 - 02/2003
6	Neoplasms (Cancer) 12/2021 - 10/2008
6	Necrosis 10/2018 - 06/2014
5	Infections 10/2016 - 01/2003
5	Malnutrition (Nutritional Deficiencies) 02/2014 - 02/2003
4	Inflammation (Inflammations) 06/2022 - 02/2014
4	Ulcer 01/2020 - 03/2011
3	Body Weight (Weight, Body) 01/2021 - 07/2004
2	Acne Vulgaris 01/2022 - 02/2014
2	Short Bowel Syndrome 01/2021 - 03/2011
2	Hemorrhage 12/2020 - 03/2011
2	Venous Thrombosis (Deep-Vein Thrombosis) 12/2020 - 01/2011
2	Dehydration (Water Stress) 01/2020 - 01/2011
2	Deglutition Disorders (Dysphagia) 04/2015 - 02/2003
2	Fatigue 10/2014 - 03/2007
2	Insulin Resistance 02/2014 - 04/2012
2	Weight Loss (Weight Reduction) 02/2014 - 03/2013
2	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 08/2012 - 03/2007
2	Liver Failure 01/2011 - 07/2008
2	Diarrhea 06/2008 - 06/2003
1	Arthralgia (Joint Pain) 01/2022
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2022
1	Nasopharyngitis 01/2022
1	Pruritus (Itching) 12/2020
1	Abdominal Hernia (Abdominal Hernias) 12/2020
1	Exanthema (Rash) 12/2020
1	Vomiting 01/2020
1	Acute Kidney Injury (Acute Renal Failure) 01/2020
1	Fever (Fevers) 01/2020
1	Disease Progression 01/2020
1	Abscess 01/2020
1	Pathologic Constriction (Stenosis) 01/2018
1	Pain (Aches) 01/2016
1	Human Influenza (Influenza) 12/2015
1	Lactose Intolerance (Intolerance, Lactose) 10/2014
1	Renal Insufficiency (Renal Failure) 08/2014
1	Neoplasm Metastasis (Metastasis) 06/2014
1	Obesity 02/2014

Drug/Important Bio-Agent (IBA)

5	C-Reactive ProteinIBA 01/2020 - 03/2014
5	Infliximab (Remicade)FDA Link 05/2016 - 01/2005
4	ontamalimabIBA 01/2022 - 01/2017
4	Pharmaceutical PreparationsIBA 12/2020 - 06/2007
3	SteroidsIBA 06/2022 - 11/2002
3	Monoclonal AntibodiesIBA 01/2022 - 10/2018
3	Adalimumab (Humira)FDA Link 01/2018 - 01/2011
3	Immunologic Factors (Immunomodulators)IBA 12/2017 - 12/2015
3	2-mercaptopurineIBA 05/2016 - 11/2009
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2016 - 06/2009
2	CytokinesIBA 05/2022 - 03/2015
2	DNA (Deoxyribonucleic Acid)IBA 12/2020 - 06/2014
2	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2020 - 12/2017
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 12/2017
2	Prednisone (Sone)FDA LinkGeneric 12/2017 - 11/2002
2	Biological ProductsIBA 11/2014 - 09/2011
2	Certolizumab Pegol FDA Link 03/2014 - 02/2013
1	GLPG0634IBA 06/2022
1	Glycoproteins (Glycoprotein)IBA 05/2022
1	Janus Kinase 1IBA 01/2022
1	Creatine Kinase (Creatine Phosphokinase)IBA 01/2022
1	Cell Adhesion Molecule-1IBA 01/2022
1	upadacitinibIBA 01/2022
1	ABX464IBA 01/2021
1	CitrullineIBA 01/2021
1	OligonucleotidesIBA 12/2020
1	Toll-Like Receptor 9IBA 12/2020
1	cobitolimodIBA 12/2020
1	Morphine (MS Contin)FDA LinkGeneric 01/2020
1	Immunosuppressive Agents (Immunosuppressants)IBA 10/2018
1	Cell Adhesion MoleculesIBA 10/2018
1	eldelumabIBA 04/2016
1	fibrin fragment D (D-dimer)IBA 01/2016
1	Influenza Vaccines (Influenza Vaccine)FDA Link 12/2015
1	Interleukin-10 (Interleukin 10)IBA 07/2015
1	InterleukinsIBA 07/2015
1	Purinergic Receptors (Receptors, Purine)IBA 03/2015
1	Adenosine Triphosphate (ATP)IBA 03/2015
1	HydrogenIBA 10/2014
1	VS 215IBA 10/2014
1	AllergensIBA 10/2014
1	Lactose FDA LinkGeneric 10/2014
1	Mesalamine (Mesalazine)FDA LinkGeneric 08/2014
1	LipidsIBA 02/2014

Therapy/Procedure

19	Therapeutics 06/2022 - 04/2008
6	Nutritional Support (Artificial Feeding) 12/2021 - 02/2003
4	Transplantation 12/2012 - 07/2006
4	Enteral Nutrition (Feeding, Tube) 06/2011 - 02/2003
3	Parenteral Nutrition 04/2015 - 07/2008
2	Radiotherapy 12/2021 - 02/2014
2	Biological Therapy 12/2020 - 10/2016
2	Gastric Bypass (Roux-en-Y Gastric Bypass) 02/2014 - 03/2013
2	Colectomy 11/2012 - 09/2011
2	Catheters 07/2012 - 01/2011
2	Home Parenteral Nutrition 08/2009 - 07/2008
1	Subcutaneous Injections 07/2022
1	Intravenous Infusions 07/2022
1	Remission Induction 01/2017
1	Aftercare (After-Treatment) 04/2015